细胞移植模型 / LNCaP

LNCaP 细胞移植模型

前列腺癌(雄激素敏感)

AR+ PSA+ 经典株(Horoszewicz 1983)。皮下(Lim 1×10⁶ / 0.25 mL Matrigel)与背叶原位(Liu 1×10⁶ / 20 μL)是两条 SOP,体积不可互换;无胶时皮下常不成瘤。不要抄 PC-3 或 MDA-MB-231。C4-2 不是亲本。RUO。

  1. [1]PMID 6831420 — LNCaP model of human prostatic carcinoma. Cancer Res (1983)
  2. [2]PMID 7681204 — Growth of an androgen-sensitive human prostate cancer cell line, LNCaP, in nude mice. Prostate (1993)
  3. [3]PMID 35168543 — Establishment of an orthotopic prostate cancer xenograft mouse model using microscope-guided orthotopic injection of LNCaP cells into the dorsal lobe of the mouse prostate. BMC Cancer (2022)
  4. [4]PMID 9108464 — A metastatic and androgen-sensitive human prostate cancer model using intraprostatic inoculation of LNCaP cells in SCID mice. Cancer Res (1997)

货号:MC-h125 · 造模页 · 体外球体

免责声明:页面内容仅供科研参考(RUO),不构成临床诊疗或动物实验操作规范。开展体内移植须取得伦理批件。文内 [n] 对应各节参考文献列表。