Cell transplantation models / BT-549
Breast carcinoma
TNBC line. s.c. locks Discov Oncol control-arm 5×10⁷ ♀ BALB/c nude; orthotopic parental not locked.
SKU: MC-h029 · Disease models
Human TNBC BT-549 s.c. CDX. This SOP uses the LONP1 paper’s control arm: 5×10⁷/mouse, ♀ BALB/c nude s.c.; μL/gel not stated. Not orthotopic fat pad. Do not copy MDA-MB-231’s 2×10⁶ / 100 μL.
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Parental orthotopic mammary fat-pad dose is not locked to a PubMed-checkable default SOP. Pilot required. Do not copy s.c. 5×10⁷.
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Red [Non-metastatic] = local tumorigenesis, not a distant-met endpoint; [Weak metastasis evidence] = poorly supported for parental line—exploratory/negative-control use.